Translational Pharmacokinetic/Pharmacodynamic Model for mRNA-3927, an Investigational Therapeutic for the Treatment of Propionic Acidemia
Author:
Affiliation:
1. Moderna, Inc., Cambridge, Massachusetts, USA.
2. Pumas AI, Inc., Centreville, Virginia, USA.
Publisher
Mary Ann Liebert Inc
Subject
Drug Discovery,Genetics,Molecular Biology,Molecular Medicine,Biochemistry
Link
https://www.liebertpub.com/doi/pdf/10.1089/nat.2022.0036
Reference16 articles.
1. Usefulness of biochemical parameters in decision-making on the start of emergency treatment in patients with propionic acidemia
2. Propionyl-CoA carboxylase – A review
3. Overview of mutations in thePCCA andPCCB genes causing propionic acidemia
4. Crystal structure of the α6β6 holoenzyme of propionyl-coenzyme A carboxylase
5. Characterization of Four Variant Forms of Human Propionyl-CoA Carboxylase Expressed in Escherichia coli
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