An Internal Polyadenylation Signal Substantially Increases Expression Levels of Lentivirus-Delivered Transgenes but Has the Potential to Reduce Viral Titer in a Promoter-Dependent Manner-Reference-Cited by-同舟云学术

An Internal Polyadenylation Signal Substantially Increases Expression Levels of Lentivirus-Delivered Transgenes but Has the Potential to Reduce Viral Titer in a Promoter-Dependent Manner

Published:2008-08 Issue:8 Volume:19 Page:840-850
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Hager Stefanie¹,Frame Fiona M.¹,Collins Anne T.¹,Burns Julie E.¹,Maitland Norman J.¹

Affiliation:

1. YCR Cancer Research Unit, Department of Biology, University of York, Heslington, York YO10 5DD, United Kingdom.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/hum.2007.165

Reference50 articles.

1. Effect of internal viral sequences on the utility of retroviral vectors

2. Expression of complete chicken thymidine kinase gene inserted in a retrovirus vector.

3. Expanding the Spectrum of Genetic Elements Transferable by Retroviral Vectors

4. Enhanced gene expression from retroviral vectors

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