Effect of internal viral sequences on the utility of retroviral vectors-Reference-Cited by-同舟云学术

Effect of internal viral sequences on the utility of retroviral vectors

Published:1987-05 Issue:5 Volume:61 Page:1647-1650
ISSN:0022-538X
Container-title:Journal of Virology
language:en
Short-container-title:J Virol

Author:

Armentano D,Yu S F,Kantoff P W,von Ruden T,Anderson W F,Gilboa E

Abstract

Expression of the human ADA cDNA encoded by the Moloney murine leukemia virus spliced RNA form is enhanced by intron-contained sequences. The presence of sequences corresponding to the viral gag gene in a Moloney murine leukemia virus-based vector results in the generation of 10- to 40-fold higher titers of virus.

Publisher

American Society for Microbiology

Subject

Virology,Insect Science,Immunology,Microbiology

Link

https://journals.asm.org/doi/pdf/10.1128/jvi.61.5.1647-1650.1987

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