Cross-Presentation of Adeno-Associated Virus Serotype 2 Capsids Activates Cytotoxic T Cells But Does Not Render Hepatocytes Effective Cytolytic Targets
Author:
Affiliation:
1. Gene Therapy Program, Department of Pathology and Laboratory Medicine, Division of Transfusion Medicine, University of Pennsylvania, Philadelphia, PA 19104.
Publisher
Mary Ann Liebert Inc
Subject
Genetics,Molecular Biology,Molecular Medicine
Link
http://www.liebertpub.com/doi/pdf/10.1089/hum.2007.001
Reference18 articles.
1. A Single-Step Affinity Column for Purification of Serotype-5 Based Adeno-associated Viral Vectors
2. Cutting Edge: Rapid In Vivo Killing by Memory CD8 T Cells
3. Determination of Specific CD4 and CD8 T Cell Epitopes after AAV2- and AAV8-hF.IX Gene Therapy
4. Humoral Immunity to Adeno-Associated Virus Type 2 Vectors following Administration to Murine and Nonhuman Primate Muscle
5. The liver as a site of T-cell apoptosis: graveyard, or killing field?
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