Mitochondrial Gene Therapy Augments Mitochondrial Physiology in a Parkinson's Disease Cell Model-Reference-Cited by-同舟云学术

Mitochondrial Gene Therapy Augments Mitochondrial Physiology in a Parkinson's Disease Cell Model

Published:2009-08 Issue:8 Volume:20 Page:897-907
ISSN:1043-0342
Container-title:Human Gene Therapy
language:en
Short-container-title:Human Gene Therapy

Author:

Keeney Paula M.¹,Quigley Caitlin K.¹,Dunham Lisa D.¹,Papageorge Christina M.¹,Iyer Shilpa¹,Thomas Ravindar R.¹,Schwarz Kathleen M.¹,Trimmer Patricia A.¹,Khan Shaharyar M.²,Portell Francisco R.²,Bergquist Kristen E.¹,Bennett James P.¹

Affiliation:

1. Morris K. Udall Parkinson's Disease Research Center of Excellence, University of Virginia, Charlottesville, VA 22908.

2. Gencia, Charlottesville, VA 22903.

Publisher

Mary Ann Liebert Inc

Subject

Genetics,Molecular Biology,Molecular Medicine

Link

http://www.liebertpub.com/doi/pdf/10.1089/hum.2009.023

Reference42 articles.

1. Surveyor™ Nuclease: A new strategy for a rapid identification of heteroplasmic mitochondrial DNA mutations in patients with respiratory chain defects

2. Rapid identification of unknown heteroplasmic mutations across the entire human mitochondrial genome with mismatch-specific Surveyor Nuclease

3. High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease

4. Dopaminergic midbrain neurons are the prime target for mitochondrial DNA deletions

5. The Layered Structure of Human Mitochondrial DNA Nucleoids

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