Possibilities of transient and two-dimensional shear wave elastography in the diagnosis of fibrosis in chronic diffuse liver diseases of non-viral etiology

Abstract

The aim of the research: to study the possibilities of transient and two-dimensional shear wave elastography in the diagnosis of fibrosis in chronic diffuse liver diseases of non-viral etiologyMaterials and methods: the study included 415 male patients aged 19 to 54 years (average age 40.4 ± 7.8 years), including 156 with non-alcoholic fatty liver disease, 66 with alcoholic liver disease, 122 with fatty disease liver alcohol-metabolic etiology, 68 people without liver disease. The examination plan included the measurement of anthropometric indicators, a biochemical study of blood serum, an ultrasound study of the hepatobiliary zone, a morphological study of liver tissue, transient and two-dimensional shear wave elastography.Results: according to the results of transient and two-dimensional shear wave elastography, the degree of fibrotic changes with combined alcohol-metabolic liver disease is higher than with isolated exposure to an alcoholic or metabolic factor; the highest diagnostic significance in elastographic research methods was noted in the third and fourth stages of fibrosis, in the second stage, the quality of the diagnostic model in transient elastography was higher than in two-dimensional shear wave.