Acute Aortic Dissection Managed with Nafamostat for Heparin Resistance in the Presence of DOAC Reversal Agent: a Case Report
Author:
Affiliation:
1. Department of Cardiovascular Surgery, Tottori Prefectural Central Hospital
Publisher
The Japanese Society for Cardiovascular Surgery
Link
https://www.jstage.jst.go.jp/article/jjcvs/53/3/53_127/_pdf
Reference14 articles.
1. 1) Lu G, DeGuzman FR, Hollenbach SJ et al. A specific antidote for reversal of anticoagulation by direct and indirect inhibitors of coagulation factor Xa. Nat Med 2013; 19: 446-51.
2. 2) Victor MN, Abdullah B, Nathan D et al. Coagulopathy management of an acute type A aortic dissection in a patient taking apixaban. J Cardiothorac Vasc Anesth 2022; 36: 1720-5.
3. 3) Yajima T, Higashimori M, Takata C et al. Andexanet alfa (ONDEXXYA® for Intravenous Injection 200 mg), a reversal agent for direct factor Xa inhibitors: pharmacological characteristics and clinical evidence. Folia Pharmacol Jpn 2023; 158: 89-100.
4. 4) Yeh CH, Fredenburgh JC, Weitz JI. The real decoy: an antidote for factor Xa-directed anticoagulants. Circ Res 2013; 113: 954-7.
5. 5) Pine P, Lu G, Canivel D et al. Andexanet alfa reverses anticoagulation effects of enoxaparin and associated bleeding in a rabbit acute hemorrhage model. Blood 2016; 128: 1445.
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