Decrease in NADPH-Cytochrome P450 Reductase Activity of the Human Heart, Liver and Lungs in the Presence of Alpha-Lipoic Acid
Author:
Publisher
S. Karger AG
Subject
Nutrition and Dietetics,Medicine (miscellaneous)
Reference31 articles.
1. Reduction of adriamycin to a semiquinone-free radical by NADPH cytochrome P-450 reductase produces DNA cleavage in a reaction mediated by molecular oxygen.
2. Reduction of paraquat and related bipyridylium compounds to free radical metabolites by rat hepatocytes
3. Importance of P450 reductase activity in determining sensitivity of breast tumour cells to the bioreductive drug, tirapazamine (SR 4233)
4. Selective Potentiation of the Hypoxic Cytotoxicity of Tirapazamine by Its 1-N-Oxide Metabolite SR 4317
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