Effect of Lumbricus terrestris Earthworm Extract and Coelomic Fluid on Some Pathogenic Bacteria

Abstract

The research aims to find natural alternatives that can inhibit the growth of types of pathogenic bacteria that have become resistant to antibiotics. Lumbricus terrestris is one of the most common worms in the world. In this study, extracts of the bodies of earthworms L. terrestris are used against different types of bacteria isolated from different disease states. Effective antibacterial chemical compounds have also been using L. terrestris extract by technique Gc-mass, which showed the presence of the compound Thiodiglycol in the rate of (43.38%) and the compound s-(2-Aminoethyl)-L-cysteine ( 22.11%), As well as the compound Dimethylamine in the rate of ( 21.20%). As well as the compound methylthio phosphonamidic acid at the rate of (3.85%). While the FTIR assay showed in its analysis that the active groups containing the hydroxyl group OH and the amide group C = O, When using methanol and acetone solvent for worm extract, it gave a high inhibitory activity at a concentration of 6.2 mg/ml, reaching (22, 30) mm when S. typhia was treated with the two solvents. We conclude from the study that earthworms contain compounds that can inhibit bacterial growth better than antibiotics. Keywords: Lumbricus terrestris, Coelomic Fluid, Gc mass, Lumbricus, Extract antibacterial.