Relationship between IL-6 gene polymorphism rs1800796 and IL-6 serum level with thyroid Hormones in a sample of Iraqi celiac disease patients.-Reference-Cited by-同舟云学术

Relationship between IL-6 gene polymorphism rs1800796 and IL-6 serum level with thyroid Hormones in a sample of Iraqi celiac disease patients.

Published:2023-10-15 Issue:CSS 4 Volume:8 Page:1-10
ISSN:1390-9347
Container-title:Sumer 4
language:
Short-container-title:RB

Author:

Ali Abd AL-Hussein Shams¹,Ahmed Jasim Hamssa²

Affiliation:

1. Department of Medical Laboratory Techniques, Al-Esraa University Collage, Bagdad, Iraq, 2 Institute of Genetic Engineering and Biotechnology for Postgraduate, University of Baghdad, Iraq

2. Institute of Genetic Engineering and Biotechnology for Postgraduate, University of Baghdad, Iraq

Abstract

Celiac disease (CD) is an autoimmune human leukocyte antigen HLA–linked enteropathy that develops upon ingesting a gluten-containing diet, with diarrhea, malabsorption, and weight loss as a major presentation. The disease is closely linked to a number of extra-intestinal disorders, especially endocrine diseases. This study aimed to find the Relationship between IL-6 gene polymorphism rs1800796 and IL-6 serum level with thyroid Hormones in a sample of Iraqi celiac disease patients. The study includes one hundred subjects of Iraqi people in Baghdad (20-60 years) who were divided into two groups; the first group included patients, and the second group control; DNA was extracted, then the Genotyping polymorphism (rs1800796) of the IL-6 gene was done by RT-PCR. The CC genotype showed a higher frequency in the control, while the GG genotype showed a higher frequency in the patients. Keywords: celiac disease (CD), genetic polymorphism IL-6gene, thyroid stimulation hormone.

Publisher

Clinical Biotec

Subject

Infectious Diseases,Applied Microbiology and Biotechnology,Epidemiology,Biotechnology

Reference121 articles.

1. 1 Singh, P.; Arora, A.; Strand, T. A.; Leffler, D. A.; Catassi, C.; Green, P. H., et al. (2018). Global

2. Prevalence of Celiac Disease: Systematic Review and Meta-analysis. Clinical gastroenterology and

3. hepatology: the official clinical practice journal of the American Gastroenterological Association, 16(6),

4. 823–836.

5. 2 Rubio-Tapia, A.; Hill, I. D.; Kelly, C. P.; Calderwood, A. H.; Murray, J. A. and American College of

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1. Relationship between IL-6 gene polymorphism rs1800796 and IL-6 serum level with thyroid Hormones in a sample of Iraqi celiac disease patients.;Sumer 4;2023-10-15