1. Department of Women’s and Children’s Health, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom;
2. Centre for Statistics in Medicine, University of Oxford, Oxford, United Kingdom;
3. Department of Clinical Epidemiology and Biostatistics, VU University Medical Centre, Amsterdam, Netherlands;
4. All-Ireland Hub for Trials Methodology Research, Centre for Public Health, Queen's University Belfast, Belfast, Northern Ireland;
5. School of Public Health, University of Sydney, Sydney, Australia;
6. Clinical Pharmacology Unit, G. Gaslini Institute, Genoa, Italy;
7. Department of Pediatrics, Santa Maria Hospital, Laboratory of Clinical Pharmacology and Therapeutics, Faculty of Medicine, Instituto de Medicina Molecular, Lisboa, Portugal;
8. Department of Pediatrics, Alberta Research Centre for Health Evidence, University of Alberta, Edmonton, Alberta, Canada;
9. Department of Anaesthesia and Pain Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada;
10. Department of Pediatric Neurology, Frenchay Hospital and the Bristol Royal Hospital for Children, Bristol, United Kingdom;
11. Department of Pediatrics and Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario, Canada;
12. Department of Medicine, University of Ottawa and Institute of Population Health, Ottawa, Ontario, Canada;
13. Child Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada; and
14. Department of Biostatisics, Institute of Translational Medicine, University of Liverpool, Liverpool, United Kingdom