Research Methods: Diagnostic Test Characteristics

Author:

Mediratta Rishi P.1,Newman Thomas B.2,Wang Marie E.1

Affiliation:

1. aDivision of Pediatric Hospital Medicine, Stanford University School of Medicine, Palo Alto, California

2. bDepartments of Epidemiology & Biostatistics and Pediatrics, University of California, San Francisco, San Francisco, California

Abstract

The goal of a diagnostic test is to provide information on the probability of disease. In this article, we review the principles of diagnostic test characteristics, including sensitivity, specificity, positive and negative predictive value, receiver operating characteristics curves, likelihood ratios, and interval likelihood ratios. We illustrate how interval likelihood ratios optimize the information that can be obtained from test results that can take on >2 values, how they are reflected in the slope of the receiver operating characteristics curve, and how they can be easily calculated from published data.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics,General Medicine,Pediatrics, Perinatology and Child Health

Reference14 articles.

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2. Why clinicians overtest: development of a thematic framework;Lam;BMC Health Serv Res,2020

3. Evidence-Based Diagnosis

4. Evidence-based emergency medicine/editorial. The problem with sensitivity and specificity;Gallagher;Ann Emerg Med,2003

5. Receiver operating characteristic (ROC) curve analysis for medical diagnostic test evaluation;Hajian-Tilaki;Caspian J Intern Med,2013

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Navigating test accuracy metrics used in diagnostic evaluation;Current Opinion in Epidemiology and Public Health;2024-07-04

2. Receiver Operating Characteristic (ROC) Curves: The Basics and Beyond;Hospital Pediatrics;2024-06-27

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