Update on Erythropoiesis-Stimulating Agents Administered to Neonates for Neuroprotection-Reference-Cited by-同舟云学术

Update on Erythropoiesis-Stimulating Agents Administered to Neonates for Neuroprotection

Published:2019-11-01 Issue:11 Volume:20 Page:e622-e635
ISSN:1526-9906
Container-title:NeoReviews
language:en
Short-container-title:

Author:

Maxwell Jessie R.¹,Ohls Robin K.²

Affiliation:

1. Department of Pediatrics, University of New Mexico, Albuquerque, NM

2. Department of Pediatrics, University of Utah, Salt Lake City, UT

Abstract

Erythropoiesis-stimulating agents (ESAs) such as erythropoietin and darbepoetin have been studied as red blood cell growth factors in preterm and term infants for more than 30 years. Recently, studies have focused on the potential neuroprotective effects of ESAs. In this review, we summarize preclinical animal models and recent clinical trials that provide evidence for ESAs as potential treatments to improve neurodevelopmental outcomes in preterm and term infants.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology and Child Health

Link

https://publications.aap.org/neoreviews/article-pdf/20/11/e622/821475/neoreviews_032019rev00036.pdf

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5. Adverse neural effects of delayed, intermittent treatment with rEPO after asphyxia in preterm fetal sheep;The Journal of Physiology;2021-06-18