Brugada Syndrome Masquerading as Febrile Seizures-Reference-Cited by-同舟云学术

Brugada Syndrome Masquerading as Febrile Seizures

Published:2007-05-01 Issue:5 Volume:119 Page:e1206-e1211
ISSN:0031-4005
Container-title:Pediatrics
language:en
Short-container-title:

Author:

Skinner Jonathan Robert¹²,Chung Seo-Kyung²³,Nel Carey-Anne²⁴,Shelling Andrew Neil²⁴,Crawford Jackie Robyn¹²,McKenzie Neil⁵,Pinnock Ralph⁶,French John Kerswell²⁷,Rees Mark Ian²⁸

Affiliation:

1. Greenlane Paediatric and Congenital Cardiac Services

2. Cardiac Inherited Disease Group, Auckland City Hospital, Grafton, Auckland, New Zealand

3. Departments of Molecular Medicine

4. Obstetrics and Gynaecology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand

5. Department of Paediatrics, Christchurch Public Hospital, Christchurch, New Zealand

6. Department of Paediatrics, Starship Children's Hospital, Grafton, Auckland, New Zealand

7. Department of Cardiology, Liverpool Hospital, Liverpool, New South Wales, Australia

8. Molecular Neuroscience Group, School of Medicine, University of Wales Swansea, Swansea, United Kingdom

Abstract

Fever can precipitate ventricular tachycardia in adults with Brugada syndrome, but such a link has not been reported in children. A 21-month-old white girl presented repeatedly with decreased conscious level and seizures during fever. During a typical episode, rapid ventricular tachycardia was documented. The resting 12-lead electrocardiogram revealed a Brugada electrocardiogram signature. Resting electrocardiograms of the asymptomatic brother and mother were normal, but fever in the mother and pharmacologic stress with ajmaline in the brother revealed Brugada electrocardiogram features. Genetic testing revealed an SCN5A mutation in the affected family members.

Publisher

American Academy of Pediatrics (AAP)

Subject

Pediatrics, Perinatology and Child Health

Link

https://publications.aap.org/pediatrics/article-pdf/119/5/e1206/1119555/zpe005070e1206.pdf

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