Author:
Klos K. J.,Ahlskog J. E.,Josephs K. A.,Apaydin H.,Parisi J. E.,Boeve B. F.,DeLucia M. W.,Dickson D. W.
Abstract
The authors assessed the frequency of spinal cord α-synuclein pathology in neurologically asymptomatic individuals older than 60 years of age (N = 106). Using α-synuclein immunohistochemistry, nine cases (8%) had incidental Lewy neurites in the intermediolateral column and at least some α-synuclein pathology in the dorsal motor nucleus of the vagus, locus ceruleus, and central raphe nucleus. Sparse α-synuclein pathology was also detected in the substantia nigra, basal forebrain, amygdala, or cortex in all but two cases.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Cited by
107 articles.
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