Maternal Stroke

Author:

Elgendy Islam Y.1ORCID,Bukhari Syed2,Barakat Amr F.2ORCID,Pepine Carl J.3ORCID,Lindley Kathryn J.4,Miller Eliza C.5ORCID,

Affiliation:

1. Division of Cardiology, Weill Cornell Medicine-Qatar, Doha (I.Y.E.).

2. Heart and Vascular Institute, University of Pittsburgh Medical Center, PA (S.B., A.F.B.).

3. Division of Cardiovascular Medicine, University of Florida, Gainesville (C.J.P.).

4. Cardiovascular Division, Department of Medicine, Washington University School of Medicine, St Louis, MO (K.J.L.).

5. Department of Neurology, Division of Stroke and Cerebrovascular Disease, Columbia University Vagelos College of Physicians and Surgeons, New York, NY (E.C.M.).

Abstract

Maternal mortality rates have been steadily increasing in the United States, and cardiovascular mortality is the leading cause of death among pregnant and postpartum women. Maternal stroke accounts for a significant burden of cardiovascular mortality. Data suggest that rates of maternal stroke have been increasing in recent years. Advancing maternal age at the time of birth and the increasing prevalence of traditional cardiovascular risk factors, and other risk factors, as well, such as hypertensive disorders of pregnancy, migraine, and infections, may contribute to increased rates of maternal stroke. In this article, we provide an overview of the epidemiology of maternal stroke, explore mechanisms that may explain increasing rates of stroke among pregnant women, and identify key knowledge gaps for future investigation in this area.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference98 articles.

1. Trends in maternal mortality 2000 to 2017: estimates by WHO UNICEF UNFPA World Bank Group and the United Nations Population Division. World Health Organization2019Accessed November 17 2020. https://apps.who.int/iris/handle/10665/327596.

2. Recent Increases in the U.S. Maternal Mortality Rate

3. Global, regional, and national levels of maternal mortality, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

4. Vital Signs: Pregnancy-Related Deaths, United States, 2011–2015, and Strategies for Prevention, 13 States, 2013–2017

5. National Vital Statistics System. Leading causes of death. Accessed September 1 2020. https://www.cdc.gov/nchs/nvss/leading-causes-of-death.htm

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