1. From Duke University Medical Center and Health System DUMC (V.J.D.), Durham, NC; Harvard Medical School and Brigham and Women’s Hospital (E.M.A., J.E.M., J.P., J.J.P., W.S.), Boston, Mass; Rush University Medical Center, Chicago, Ill (H.R.B.); and the Mayo Clinic and Mayo Clinic Foundation, Mayo College of Medicine, Rochester, Minn (D.L.H.).