Cardiovascular, Bleeding, and Mortality Risks in Elderly Medicare Patients Treated With Dabigatran or Warfarin for Nonvalvular Atrial Fibrillation

Author:

Graham David J.1,Reichman Marsha E.1,Wernecke Michael1,Zhang Rongmei1,Southworth Mary Ross1,Levenson Mark1,Sheu Ting-Chang1,Mott Katrina1,Goulding Margie R.1,Houstoun Monika1,MaCurdy Thomas E.1,Worrall Chris1,Kelman Jeffrey A.1

Affiliation:

1. From the Office of Surveillance and Epidemiology (D.J.G., M.E.R., K.M., M.R.G., M.H.), Office of Biostatistics (R.Z., M.L.), and Office of New Drugs (M.R.S.), Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, MD; Acumen LLC, Burlingame, CA (M.W., T.S., T.E.M.); Department of Economics, Stanford University, Stanford, CA (T.E.M.); and Centers for Medicare & Medicaid Services, Washington, DC (C.W., J.A.K.).

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference34 articles.

1. Oral anticoagulants for preventing stroke in patients with non-valvular atrial fibrillation and no previous history of stroke or transient ischemic attacks.;Aguilar MI;Cochrane Database Syst Rev,2005

2. Stroke prevention with aspirin, warfarin and ximelagatran in patients with non-valvular atrial fibrillation: A systematic review and meta-analysis

3. Meta-analysis: Antithrombotic Therapy to Prevent Stroke in Patients Who Have Nonvalvular Atrial Fibrillation

4. Warfarin Anticoagulation and Outcomes in Patients With Atrial Fibrillation

5. Product label for Pradaxa (dabigatran etexilate mesylate). http://www.accessdata.fda.gov/drugsatfda_docs/label/2012/022512s011lbl.pdf. Accessed July 3 2012.

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