The Impact of Sex and Gender on Stroke-Reference-Cited by-同舟云学术

The Impact of Sex and Gender on Stroke

Published:2022-02-18 Issue:4 Volume:130 Page:512-528
ISSN:0009-7330
Container-title:Circulation Research
language:en
Short-container-title:Circ Res

Author:

Rexrode Kathryn M.¹^ORCID,Madsen Tracy E.²³^ORCID,Yu Amy Y.X.⁴^ORCID,Carcel Cheryl⁵^ORCID,Lichtman Judith H.⁶^ORCID,Miller Eliza C.⁷^ORCID

Affiliation:

1. Division of Women’s Health, Department of Medicine, Brigham and Women’s Hospital, Boston, MA (K.M.R.).

2. Division of Sex and Gender in Emergency Medicine, Department of Emergency Medicine, Warren Alpert Medical School of Brown University, Providence, RI (T.E.M.).

3. Department of Epidemiology, Brown University School of Public Health, Providence, RI (T.E.M.).

4. Department of Medicine (Neurology), University of Toronto, Sunnybrook Health Sciences Centre, Ontario, Canada (A.Y.X.Y.).

5. Neurology Program, George Institute for Global Health, University of New South Wales, Sydney, Australia (C.C.).

6. Department of Chronic Disease Epidemiology, Yale School of Public Health, New Haven, CT (J.H.L.).

7. Division of Stroke and Cerebrovascular Disease, Department of Neurology, Columbia University Vagelos College of Physicians and Surgeons, New York, NY (E.C.M.).

Abstract

Women face a disproportionate burden of stroke mortality and disability. Biologic sex and sociocultural gender both contribute to differences in stroke risk factors, assessment, treatment, and outcomes. There are substantial differences in the strength of association of stroke risk factors, as well as female-specific risk factors. Moreover, there are differences in presentation, response to treatment, and stroke outcomes in women. This review outlines current knowledge of impact of sex and gender on stroke, as well as delineates research gaps and areas for future inquiry.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

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