Sino-MONICA Project

Author:

Wu Zhaosu1,Yao Chonghua1,Zhao Dong1,Wu Guixian1,Wang Wei1,Liu Jing1,Zeng Zhechun1,Wu Yingkai1

Affiliation:

1. From the Beijing Institute of Heart, Lung, and Blood Vessel Diseases, Beijing, China.

Abstract

Background —The Sino-MONICA project is a 7-year study monitoring trends and determinants of cardiovascular disease (CVD) in geographically defined populations in different parts of China. Methods and Results —The study is a community-based prospective disease surveillance that uses the methodology and criteria of the World Health Organization’s Monitoring Trends and Determinants in Cardiovascular Disease (WHO MONICA) project, with slight modifications for local use. After a pilot study of 2 years (1985 through 1986), data collection started formally on January 1, 1987, and ended on December 31, 1993. The main results were as follows. By international standards, both the incidence and mortality rate of coronary heart disease in Chinese populations were low. The highest incidence was 108.7 of 100 000 (1987 to 1989), and the lowest was 3.3 of 100 000 for men 35 to 64 years of age, a 33-fold difference. Both the incidence and mortality rate of cerebrovascular disease were high. The highest incidence was 553.3 of 100 000 (1987 to 1989), and the lowest was 33.0 of 100 000 for men 35 to 64 years of age, a 17-fold difference. There were significant geographic variations in both CVD incidence and mortality rate, with higher rates in the north and lower rates in the south. During 1987 to 1993, increasing trends were found in CVD rates in some populations, whereas decreasing trends were found in others. The trends were not significant statistically in most cases. Conclusions —Monitoring CVD with international standardized methods in China is feasible and urgently needed in view of the rapid socioeconomic development and transition of disease patterns taking place in China. The results are of significance in combating CVD both at home and abroad.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference12 articles.

1. Proposal for the Multinational Monitoring of Trends and Determinants in Cardiovascular Diseases and Protocol (MONICA Project) . Geneva Switzerland: World Health Organization Cardiovascular Disease Unit; 1983.

2. Wu ZS Yao CH Chen DY et al. The Sino-MONICA-Beijing study: report on results between 1984 and 1986. Acta Med Scand . 1988;728(suppl):60–66.

3. Ecological Bias, Confounding, and Effect Modification

4. Multinational Monitoring of Trends and Determinants in Cardiovascular Diseases (MONICA Project) and Manual of Operation . Geneva Switzerland: World Health Organization Cardiovascular Disease Unit; 1983.

5. Tunstall-Pedoe H. Problems with criteria and quality control in the registration of coronary events in the MONICA study. Acta Med Scand . 1988;728(suppl):17–25.

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