Predictive etiological classification of acute ischemic stroke through interpretable machine learning algorithms: a multicenter, prospective cohort study

Author:

Chen Siding,Yang Xiaomeng,Gu Hongqiu,Wang Yanzhao,Xu Zhe,Jiang Yong,Wang Yongjun

Funder

National Natural Science Foundation of China

the Capital’s Funds for Health Improvement and Research

Chinese Academy of Medical Sciences Innovation Fund for Medical Sciences

Publisher

Springer Science and Business Media LLC

Reference54 articles.

1. Roth GA, Abate D, Abate KH, Abay SM, Abbafati C, Abbasi N, et al. Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980–2017: a systematic analysis for the global burden of Disease Study 2017. Lancet. 2018;392:1736–88.

2. Wang Y, Jing J, Meng X, Pan Y, Wang Y, Zhao X, et al. The third China National Stroke Registry (CNSR-III) for patients with acute ischaemic stroke or transient ischaemic attack: design, rationale and baseline patient characteristics. Stroke Vasc Neurol. 2019;4:158–64.

3. Wang Y-J, Li Z-X, Gu H-Q, Zhai Y, Jiang Y, Zhao X-Q, the National Center for Healthcare Quality Management in Neurological Diseases, China National Clinical Research Center for Neurological Diseases, the Chinese Stroke Association. Stroke Vasc Neurol. 2020;5:211–39. National Center for Chronic and Non-communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention and Institute for Global Neuroscience and Stroke CollaborationsChina Stroke Statistics 2019: A Report From.

4. Adams HP, Bendixen BH, Kappelle LJ, Biller J, Love BB, Gordon DL, et al. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke. 1993;24:35–41.

5. Yang X-L, Zhu D-S, Lv H-H, Huang X-X, Han Y, Wu S, et al. Etiological classification of cerebral ischemic stroke by the TOAST, SSS-TOAST, and ASCOD systems: the impact of Observer’s experience on reliability. Neurologist. 2019;24:111–4.

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