1. From the Department of Neurology, Institute of Brain Disease, Tohoku University School of Medicine, Sendai, Miyagi (Y.Y., H.S., H.O., Y.I.); the Hanno Research Center, Taiho Pharmaceutical Co Ltd, Hanno, Saitama (N.M.); and the Institute of Neuropathology, Kumagaya, Saitama (K.K.), Japan.