ACCF/AHA Clopidogrel Clinical Alert: Approaches to the FDA “Boxed Warning”

Author:

,Holmes David R.,Dehmer Gregory J.,Kaul Sanjay,Leifer Dana,O'Gara Patrick T.,Stein C. Michael

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference74 articles.

1. FDA Drug Safety Communication: reduced effectiveness of Plavix (clopidogrel) in patients who are poor metabolizers of the drug. Available at: http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm203888.htm. Accessed April 28 2010.

2. Cytochrome P450 2C19 polymorphism in young patients treated with clopidogrel after myocardial infarction: a cohort study

3. Relation of Cytochrome P450 2C19 Loss-of-Function Polymorphism to Occurrence of Drug-Eluting Coronary Stent Thrombosis

4. Cytochrome P450 2C19 loss-of-function polymorphism and stent thrombosis following percutaneous coronary intervention

5. Stockbridge N. FDA Letter of Approval: May 5 2009 NDA 20-839/S-040. U.S. Food and Drug Administration. Available at: http://www.accessdata.fda.gov/drugsatfda_docs/appletter/2009/020839s040ltr.pdf. Accessed April 29 2010.

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