Effect of Intra-arterial Insulin on Tissue Cholesterol and Fatty Acids in Alloxan-Diabetic Dogs-Reference-Cited by-同舟云学术

Effect of Intra-arterial Insulin on Tissue Cholesterol and Fatty Acids in Alloxan-Diabetic Dogs

Published:1961-01 Issue:1 Volume:9 Page:39-43
ISSN:0009-7330
Container-title:Circulation Research
language:en
Short-container-title:Circulation Research

Author:

CRUZ ANATOLIO B.¹,AMATUZIO DONALD S.¹,GRANDE FRANCISCO¹,HAY LYLE J.¹

Affiliation:

1. Jay Phillips Research Laboratory, Mount Sinai Hospital, the Departments of Medicine, Physiological Hygiene and Surgery, and the Graduate School of the University of Minnesota, Minneapolis, Minn

Abstract

Insulin and saline were injected into the right and left femoral arteries respectively of 19 alloxan-diabetes-mellitus dogs for 1 to 28 weeks. A significant increase of artery tissue cholesterol and total fatty acids was found on comparing the insulin-administered right leg with the saline-administered left leg. Similarly, a significant increase of total fatty acids in muscle was found on comparing the right with the left leg of the alloxan-diabetes mellitus dogs. No significant differences were observed in the normal animals when the insulin-injected side was compared with the noninjected.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Link

https://www.ahajournals.org/doi/pdf/10.1161/01.RES.9.1.39

Reference22 articles.

1. SKOUBY A. P.: Vascular lesion in diabetes with special References to influence of treatment. Acta med. scandinav. 155 (suppl. 317): 1 1956.

2. VAN ECK W. F.: Effects of a low fat diet on the serum lipids in diabetes and its significance in diabetic retinopathy. Am. J. iled. 27: 196 1959.

3. BRYFOGLE T. W. AND BRADLEY B.: Vascular complications of diabetes mellitus. 6: 159 1957.

4. Diabetes

5. Postmortem study of vascular disease in diabetics;BELL A. T.;A. M. A. Arch. Path.,1952

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