Chemokines Control Mobilization, Recruitment, and Fate of Monocytes in Atherosclerosis-Reference-Cited by-同舟云学术

Chemokines Control Mobilization, Recruitment, and Fate of Monocytes in Atherosclerosis

Published:2015-05 Issue:5 Volume:35 Page:1050-1055
ISSN:1079-5642
Container-title:Arteriosclerosis, Thrombosis, and Vascular Biology
language:en
Short-container-title:ATVB

Author:

Drechsler Maik¹,Duchene Johan¹,Soehnlein Oliver¹

Affiliation:

1. From the Institute for Cardiovascular Prevention, Ludwig-Maximilians-University, Munich, Germany (M.D., J.D., O.S.); Department of Pathology, Academic Medical Center Amsterdam, University of Amsterdam, Amsterdam, The Netherlands (M.D., O.S.); and German Centre for Cardiovascular Research (DZHK), Partner Site Munich Heart Alliance, Munich, Germany (M.D., O.S.).

Abstract

Atherosclerosis is a chronic inflammatory disease of large arteries and, among others, characterized by continuous influx of monocytes into the subendothelial space, subsequent macrophage accumulation, and foam cell formation. Chemokines and their receptors tightly orchestrate monocyte trafficking and fate from birth to death. This brief review summarizes our current understanding of the interplay between monocytes and chemokines entertaining crucial processes in atherosclerosis development, progression, and regression.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine

Link

https://www.ahajournals.org/doi/pdf/10.1161/ATVBAHA.114.304649

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