1. From the Department of Social Medicine (A.F., R.H., G.D.S., D.A.L.), University of Bristol, UK; BHF Glasgow Cardiovascular Research Centre (N.S.), University of Glasgow, Scotland; the Department of Epidemiology & Population Health (S.E.), London School of Hygiene & Tropical Medicine, UK; and MRC Centre for Causal Analyses in Translational Epidemiology (G.D.S., D.A.L.), University of Bristol, UK.