1. From the Division of Pulmonary, Critical Care, Sleep and Allergy, Department of Medicine, College of Medicine (A.N.R., S.M.D.) and Department of Pharmacology (A.N.R., G.P.v.N.A., S.M.D.), University of Illinois at Chicago; Departments of Physiology (J.A., G.P.v.N.A.) and Pulmonary Diseases (J.A.), Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands.