Choosing a Mouse Model of Venous Thrombosis-Reference-Cited by-同舟云学术

Choosing a Mouse Model of Venous Thrombosis

Published:2019-03 Issue:3 Volume:39 Page:311-318
ISSN:1079-5642
Container-title:Arteriosclerosis, Thrombosis, and Vascular Biology
language:en
Short-container-title:ATVB

Author:

Diaz Jose A.¹,Saha Prakash²,Cooley Brian³,Palmer Olivia R.¹,Grover Steven P.³,Mackman Nigel³,Wakefield Thomas W.¹,Henke Peter K.¹,Smith Alberto²,Lal Brajesh K.⁴

Affiliation:

1. From the Department of Surgery, Vascular Surgery, University of Michigan, Ann Arbor (J.A.D., O.R.P., T.W.W., P.K.H.)

2. Academic Department of Vascular Surgery, King’s College London, UK (P.S., A.S.)

3. Department of Medicine, Division of Hematology/Oncology, University of North Carolina at Chapel Hill (B.C., S.P.G., N.M.)

4. Department of Surgery, University of Maryland, College Park (B.K.L.).

Abstract

Murine models are widely used valuable tools to study deep vein thrombosis. Leading experts in venous thrombosis research came together through the American Venous Forum to develop a consensus on maximizing the utility and application of available mouse models of venous thrombosis. In this work, we provide an algorithm for model selection, with discussion of the advantages, disadvantages, and applications of the main mouse models of venous thrombosis. Additionally, we provide a detailed surgical description of the models with guidelines to validate surgical technique.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine

Link

https://www.ahajournals.org/doi/pdf/10.1161/ATVBAHA.118.311818

Reference53 articles.

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4. Interleukin-6: A Potential Target for Post-Thrombotic Syndrome

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