Broad Genetic Testing in a Clinical Setting Uncovers a High Prevalence of Titin Loss-of-Function Variants in Very Early Onset Atrial Fibrillation-Reference-Cited by-同舟云学术

Broad Genetic Testing in a Clinical Setting Uncovers a High Prevalence of Titin Loss-of-Function Variants in Very Early Onset Atrial Fibrillation

Published:2019-11 Issue:11 Volume:12 Page:
ISSN:2574-8300
Container-title:Circulation: Genomic and Precision Medicine
language:en
Short-container-title:Circ: Genomic and Precision Medicine

Author:

Goodyer William R.¹²,Dunn Kyla³,Caleshu Colleen³,Jackson Mary³,Wylie Jennifer³,Moscarello Tia³,Platt Julia³,Reuter Chloe³,Smith Allysonne³,Trela Anthony²,Ceresnak Scott R.²,Motonaga Kara S.²,Ashley Euan¹³⁴,Yang Phillip¹⁴,Dubin Anne M.²,Perez Marco¹³⁴

Affiliation:

1. Cardiovascular Institute, Stanford University (W.R.G., E.A., P.Y., M.P.).

2. Division of Pediatric Cardiology, Department of Pediatrics, Lucille Packard Children’s Hospital (W.R.G., A.T., S.R.C., K.S.M., A.M.D.).

3. Stanford Center for Inherited Cardiovascular Disease (K.D., C.C., M.J., J.W., T.M., J.P., C.R., A.S., E.A., M.P.).

4. Division of Cardiovascular Medicine, Department of Medicine, Stanford University School of Medicine, CA (E.A., P.Y., M.P.).

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

General Medicine

Reference6 articles.

1. Worldwide Epidemiology of Atrial Fibrillation

2. Very early-onset lone atrial fibrillation patients have a high prevalence of rare variants in genes previously associated with atrial fibrillation

3. Atrial fibrillation without comorbidities: Prevalence, incidence and prognosis (from the Framingham Heart Study)

4. Atrial Fibrillation Begets Heart Failure and Vice Versa

5. Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation

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