Adoption of Transradial Percutaneous Coronary Intervention and Outcomes According to Center Radial Volume in the Veterans Affairs Healthcare System

Author:

Gutierrez Antonio1,Tsai Thomas T.1,Stanislawski Maggie A.1,Vidovich Mladen1,Bryson Christopher L.1,Bhatt Deepak L.1,Grunwald Gary K.1,Rumsfeld John1,Rao Sunil V.1

Affiliation:

1. From the Brigham and Women’s Hospital, Harvard Medical School, Boston, MA (A.G., D.L.B.); VA Eastern Colorado Healthcare System, University of Colorado Denver, Aurora, CO (T.T.T., M.A.S., G.K.G., J.R.), VA Medical Center, University of Illinois at Chicago (M.V.); Seattle VA Medical Center, Seattle, WA (C.L.B.), VA Boston Healthcare System, West Roxbury, MA (D.L.B.); and Durham VA Medical Center, Duke Clinical Research Institute, Durham, NC (S.V.R.).

Abstract

Background— Studies examining the association between radial approach and post–percutaneous coronary intervention (PCI) bleeding and mortality have reached conflicting conclusions. There are no current data about the use and outcomes of transradial PCI (r-PCI) in the Veterans Affairs system. Methods and Results— Consecutive veterans (n=24 143 patients) undergoing PCI in the Veterans Affairs between 2007 and 2010 were examined. On the basis of propensity to undergo r-PCI, 3 cohorts matched with veterans undergoing transfemoral access were constructed among sites performing ≥1 r-PCI, ≥50 r-PCI (high volume), and <50 r-PCI (low volume). Cox proportional hazard models were used to determine the association between PCI access site, blood transfusion, and mortality. The prevalence of r-PCI increased over time (2007=2.1%; 2010=8.8%). Overall, there was no difference in procedure success between matched groups (r-PCI 97.3% versus transfemoral PCI 96.6%; P =0.182), or in the risk of postprocedure transfusion or mortality. Among matched patients treated at high r-PCI volume sites, radial access was associated with a decreased risk of post-PCI blood transfusion (hazard ratio, 0.4; 95% confidence interval, 0.3–0.7; P <0.001), and no significant difference in the risk of mortality (hazard ratio, 0.7; 95% confidence interval, 0.4–1.3; P =0.279). Conclusions— Within the Veterans Affairs, the use of r-PCI increased over time. r-PCI may be associated with a significant decreased risk of post-PCI blood transfusion among higher volume r-PCI sites. These data demonstrate that potential benefits of r-PCI in terms of reduced post-PCI blood transfusions may be more pronounced at sites that routinely use radial access.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine

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