Pulsus Alternans in Cardiogenic Shock Recapitulated in Single Cell Fluorescence Imaging of a Patient’s Cardiomyocyte

Author:

Moreno Jonathan D.1ORCID,Bhagavan Druv2ORCID,Li Allie1ORCID,Gerstner Nels C.3ORCID,Miller Evan W.3ORCID,Huebsch Nathaniel2,Cresci Sharon14ORCID,Silva Jonathan R.2ORCID

Affiliation:

1. Division of Cardiology, Department of Medicine, Washington University, St. Louis, MO. (J.D.M., A.L., S.C.)

2. Department of Biomedical Engineering, Washington University, St. Louis, MO. (D.B., N.H., J.R.S.)

3. Departments of Chemistry and Molecular & Cell Biology, University of California, Berkeley (N.C.G., E.W.M.).

4. Washington University School of Medicine, St. Louis, MO (S.C.).

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine

Reference10 articles.

1. Cardiac alternans: mechanisms and pathophysiological significance;Euler DE;Cardiovasc Res.,1999

2. Isolation and functional characterization of human ventricular cardiomyocytes from fresh surgical samples;Coppini R;J Vis Exp.,2014

3. A modified method for isolation of human cardiomyocytes to model cardiac diseases;Guo GR;J Transl Med.,2018

4. A photostable silicon rhodamine platform for optical voltage sensing;Huang YL;J Am Chem Soc.,2015

5. Instability and triangulation of the action potential predict serious proarrhythmia, but action potential duration prolongation is antiarrhythmic;Hondeghem LM;Circulation.,2001

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