1. From the Department of Molecular Cardiology, Texas Heart Institute, Houston (L.Z., P.V., J.T.W., R.A.F.D.); Department of Medicine (Cardiology), University of Texas-Houston Medical School (Z.C., J.T.W.); and Department of Pharmacological and Pharmaceutical Sciences, Center for Experimental Therapeutics and Pharmacoinformatics, University of Houston, Houston, TX (S.-P.S., K.-H.R.).