1. From the Office of Personalized Medicine (J.M.P., M.A.B., D.M.R.) and Center for Human Genetics Research (M.D.R., D.C.C., J.L.H.), and Departments of Biomedical Informatics (J.C.D., M.D.R., D.R.M.), Molecular Physiology and Biophysics (M.D.R., D.C.C., J.L.H.), Biostatistics (J.S.S.), Pharmacology (D.M.R.), and Medicine (J.C.D., A.H.R., D.M.R.), Vanderbilt University School of Medicine, Nashville, Tenn.