Effect of Hypertonic Saline on the Pulmonary and Systemic Pressures

Author:

ELIAKIM M.1,ROSENBERG S. Z.1,BRAUN K.1

Affiliation:

1. Cardiovascular Unit and Department of Internal Medicine, Division B, Rothschild Hadassah University Hospital, Jerusalem, Israel

Abstract

The intravenous injection of 20 per cent saline in anesthetized closed chest dogs causes a rise in pulmonary venous, pulmonary arterial, right ventricular and peripheral venous pressures. Left atrial pressure does not change or falls, and systemic arterial pressure decreases very markedly. These changes are shown to result from spasm at the pulmonary vein--left atrial junction. Stimulation of chemoreceptors in this region is assumed to be the cause of the spasm.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Reference19 articles.

1. BINET L. AND BUBSTEIN M.: Sur Faction vasoconstrictrice du serum sale hypertonique an niveau de la petite circulation. Compts. rend. soc. de Biol. 145: 1766 1951.

2. BINET L. AND BUBSTEIN M. : Sur les effets cardio-vasculaires du serum sale hypertonique. Compts. rend soc. de Biol. 147: 1997 1953.

3. Ueber quergestreifte Muskelfasern in der Wand der Lungenvenen

4. Functional anatomy and “throttle valve” action of the pulmonary veins

5. Roentgenologic studies of the sphincter mechanism of the caval and pulmonary veins

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