Determinants of Duration and Mean Rate of Ventricular Ejection

Author:

BRAUNWALD E.1,SARNOFF S. J.1,STAINSBY W. N.1

Affiliation:

1. laboratory of Cardiovascular Physiology, National Heart Institute, Bethesda, Md.

Abstract

The independent influences of stroke volume, heart rate, aortic pressure, hypothermia, sympathomimetic amines, metered mitral and aortic valvular regurgitation, and alterations in myocardial contractility on the duration and mean rate of ventricular ejection and filling were studied. These observations were made in a metabolically supported, isolated heart preparation with performance characteristics comparable to the non-isolated heart.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Reference23 articles.

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2. The specific influence of the accelerator nerves on the duration of ventricular systole;WIGGERS C. J.;Physiol.,1920

3. Am. J.

4. Interrelation between the length of systole, stroke volume and left ventricular work in the dog;REMINGTON J. W.;Am. J. Physiol.,1948

5. Studies on the consecutive phases of the cardiac cycle: II. The laws governing the relative durations of ventricular systole and diastole;WIGGERS C. J.;Am. J. Physiol.,1921

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