1. From the Department of Physiology, Institute of Fundamental and Clinical Movement Sciences (D.H.J.T., R.E., M.K., M.T.E.H.); and the Departments of Pharmacology-Toxicology (P.P., G.A.R., P.S.), Internal Medicine (G.A.R., P.S.), and Intensive Care (P.P.), Radboud University Nijmegen Medical Centre, Netherlands.