Spinal cord injury and vascular function: evidence from diameter-matched vessels-Reference-Cited by-同舟云学术

Spinal cord injury and vascular function: evidence from diameter-matched vessels

Published:2021-03-01 Issue:3 Volume:130 Page:562-570
ISSN:8750-7587
Container-title:Journal of Applied Physiology
language:en
Short-container-title:Journal of Applied Physiology

Author:

Venturelli Massimo¹²^ORCID,Amann Markus²³⁴⁵,Trinity Joel D.²³⁴⁵,Ives Stephen J.²⁴^ORCID,Richardson Russell S.²⁴⁵

Affiliation:

1. Department of Neurosciences, Biomedicine and Movement Sciences. University of Verona, Verona, Italy

2. Division of Geriatrics, Department of Internal Medicine, University of Utah, Salt Lake City, Utah

3. Department of Anesthesiology, University of Utah, Salt Lake City, Utah

4. Geriatric Research, Education, and Clinical Center, George E. Wahlen VA Medical Center, Salt Lake City, Utah

5. Department of Nutrition and Integrative Physiology, University of Utah, Salt Lake City, Utah

Abstract

This study examined the effect of a spinal cord injury (SCI) and subsequent limb disuse on vascular function, assessed by %FMD, in diameter-matched vessels above and below the lesion in subjects with SCI and controls. The results reveal normal vascular function above the lesion and vascular dysfunction below the lesion (%FMD). However, below the lesion there was, actually, evidence of increased vascular responsiveness (%FMD/shear rate) in this population.

Funder

Veterans Administration (VA) Rehabilitation Research and Development Service

HHS | NIH | National Heart, Lung, and Blood Institute

Publisher

American Physiological Society

Subject

Physiology (medical),Physiology

Link

https://journals.physiology.org/doi/pdf/10.1152/japplphysiol.00329.2020

Reference44 articles.

1. A Global Perspective on Spinal Cord Injury Epidemiology

2. Epidemiology, Demographics, and Pathophysiology of Acute Spinal Cord Injury