1. From the Gladstone Institute of Cardiovascular Disease (L.B.N., M.V., J.B., M.R., L.F., S.G.Y.), Cardiovascular Research Institute (L.B.N., M.V., J.B., M.R., S.G.Y., M.D.G., R.L.H., J.S.W., C.T.), and Departments of Medicine (S.G.Y., M.D.G.) and Anatomy (R.L.H., J.S.W.), University of California, San Francisco; and the Department of Medicine, Columbia University College of Physicians and Surgeons, New York, NY (I.J.G., T.V.-R.).