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Transgenic Mice That Overexpress Mouse Apolipoprotein B

Published:1996-05 Issue:20 Volume:271 Page:11963-11970
ISSN:0021-9258
Container-title:Journal of Biological Chemistry
language:en
Short-container-title:Journal of Biological Chemistry

Author:

McCormick Sally P.A.,Ng Jennifer K.,Véniant Murielle,Borén Jan,Pierotti Vincenzo,Flynn Laura M.,Grass David S.,Connolly Andrew,Young Stephen G.

Publisher

Elsevier BV

Subject

Cell Biology,Molecular Biology,Biochemistry

Reference18 articles.

1. Transgenic mice expressing high plasma concentrations of human apolipoprotein B100 and lipoprotein(a).

2. Expression of human apolipoprotein B and assembly of lipoprotein(a) in transgenic mice.

3. Transgenic mice expressing human apoB100 and apoB48

4. Transgenic mice expressing high levels of human apolipoprotein B develop severe atherosclerotic lesions in response to a high-fat diet.

5. Ability of the LDL receptor from several animal species to recognize the human apo B binding domain: studies with LDL from familial defective apo B-100

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