1. From the Department of Medicine and Clinical Science (H.U., M.Y., T.S., M.O., X.X., H.T., T. Oda, S.O., M.D., S.K., T.Y., Y.I., T. Ohkusa, M.M.), Division of Cardiology, Yamaguchi University Graduate School of Medicine, Japan; Boston Biomedical Research Institute (N.I.), Watertown, Mass; and Department of Neurology (N.I.), Harvard Medical School, Boston, Mass.