Mesenchymal Stem Cells as a Biological Drug for Heart Disease-Reference-Cited by-同舟云学术

Mesenchymal Stem Cells as a Biological Drug for Heart Disease

Published:2015-07-17 Issue:3 Volume:117 Page:229-233
ISSN:0009-7330
Container-title:Circulation Research
language:en
Short-container-title:Circ Res

Author:

Sanina Cristina¹,Hare Joshua M.¹

Affiliation:

1. From the Interdisciplinary Stem Cell Institute (C.S., J.M.H.), Department of Medicine, Division of Cardiology (J.M.H.), and Department of Molecular and Cellular Pharmacology, University of Miami Miller School of Medicine, FL (J.M.H.).

Abstract

Cell-based treatment represents a new generation in the evolution of biological therapeutics. A prototypic cell-based therapy, the mesenchymal stem cell, has successfully entered phase III pivotal trials for heart failure, signifying adequate enabling safety and efficacy data from phase I and II trials. Successful phase III trials can lead to approval of a new biological therapy for regenerative medicine.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Cardiology and Cardiovascular Medicine,Physiology

Link

https://www.ahajournals.org/doi/pdf/10.1161/CIRCRESAHA.117.306306

Reference23 articles.

1. Use of Mesenchymal Stem Cells for Therapy of Cardiac Disease

2. Discrepancies in autologous bone marrow stem cell trials and enhancement of ejection fraction (DAMASCENE): weighted regression and meta-analysis

3. The MSC: An Injury Drugstore

4. Bone Marrow Mononuclear Cell Therapy and Granulocyte Colony-Stimulating Factor for Acute Myocardial Infarction

5. Mesenchymal Stem Cells

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