1. From the Laboratory of Surgical Research, Departments of Anesthesia and Surgery (M.T.G., J.R., B.M., M.H., J.-F.P.), Department of Medicine, The Cardiovascular Research Institute (J.A.F., M.A.M., J.-F.P.), Lung Biology Center (G.S., D.S.), University of California, San Francisco; and Department of Exploratory Biology (S.M.V., P.H.W., G.S.H.), Biogen Idec, Cambridge, Mass.