Lung Fibrosis Is Linked to Increased Endothelial Cell Activation and Dysfunctional Vascular Barrier Integrity

Author:

Fließer Elisabeth1ORCID,Jandl Katharina12,Lins Thomas1,Birnhuber Anna13ORCID,Valzano Francesco1,Kolb Dagmar45,Foris Vasile6,Heinemann Akos2,Olschewski Horst6ORCID,Evermann Matthias7,Hoetzenecker Konrad7,Kreuter Michael89,Voelkel Norbert F.1011,Marsh Leigh M.13ORCID,Wygrecka Malgorzata1213,Kwapiszewska Grazyna1313

Affiliation:

1. Ludwig Boltzmann Institute for Lung Vascular Research, Graz, Austria;

2. Division of Pharmacology and

3. Lung Group, Otto Loewi Research Center,

4. Core Facility Ultrastructural Analysis,

5. Gottfried Schatz Research Center, Cell Biology, Histology, and Embryology, and

6. Division of Pulmonology, Department of Internal Medicine, Medical University of Graz, Graz, Austria;

7. Department of Thoracic Surgery, Medical University of Vienna, Vienna, Austria;

8. Mainz Center for Pulmonary Medicine, Department of Pneumology, Mainz University Medical Center, Mainz, Germany;

9. Department of Pulmonary, Critical Care, and Sleep Medicine, Marienhaus Clinic Mainz, Mainz, Germany;

10. Pulmonary Medicine Department, University of Amsterdam Medical Centers, Amsterdam, the Netherlands;

11. Department of Pulmonary Medicine, Amsterdam Cardiovascular Sciences, Amsterdam University Medical Centers, Amsterdam, the Netherlands;

12. Center for Infection and Genomics of the Lung, Universities of Giessen and Marburg Lung Center, Giessen, Germany; and

13. Institute for Lung Health, Cardiopulmonary Institute, Member of the German Lung Center (DZL), Giessen, Germany

Funder

German Cardio-Pulmonary Institute

International Foundation for Functional Gastrointestinal Disorders

Deutsches Zentrum für Lungenforschung

Deutsche Forschungsgemeinschaft

Austrian Science Fund

Publisher

American Thoracic Society

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