Vital Capacity and Congestive Heart Failure

Author:

KANNEL W. B.1,SEIDMAN J. M.1,FERCHO W.1,CASTELLI W. P.1

Affiliation:

1. From the Framingham Heart Disease Epidemiology Study, Framingham, Massachusetts, the National Heart and Lung Institute, National Institutes of Health, Bethesda, Maryland, and the University of Massachusetts Medical School, Worcester, Massachusetts.

Abstract

This report is concerned with an assessment of the utility of the vital capacity in anticipating the occurrence of congestive heart failure in susceptible persons before overt symptoms and signs. To this end, an examination of the relation of routinely measured biennial vital capacities to subsequent incidence of clinically overt myocardial decompensation over the next two years was undertaken. In 5209 persons so evaluated over an 18 year period it was found that risk of congestive heart failure varied over a 10-fold range in inverse proportion to their vital capacity (standardized for height) in persons still free of clinical evidence of myocardial decompensation. Also, among persons at high risk of failure (due to coronary disease, hypertension or rheumatic heart disease) chances of developing congestive failure were doubled in men with low vital capacities and tripled in women. Examination of the net contribution of vital capacity to risk of congestive failure revealed that a low vital capacity was associated with development of congestive failure even after taking into account other contributing factors including blood pressure, relative weight, pulse rate, cigarette smoking, heart enlargement on X-ray, ECG-LVH, blood glucose and age. Both a persistently low and a recent fall in vital capacity were associated with increased risk of congestive failure. Obstructive lung disease was not a factor in either case since FEV 1 /total vital capacity (TVC) was unrelated to congestive heart failure incidence. The simple total vital capacity thus appears to have considerable utility as a practical, noninvasive office procedure for evaluating failing left ventricular performance.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Reference16 articles.

1. The value of determination of the vital capacity of the Iungs in the care of patients with heart disease;Arq Bras Cardiol,1949

2. Lung volumes. In Handbook of Physiology, edited by FENN WO, RAHN H. Washington, DC, American Physiologic Society, 1965;Section

3. The Natural History of Congestive Heart Failure: The Framingham Study

4. com.atypon.pdfplus.internal.model.plusxml.impl.AuthorGroup@163a6bf : The Framingham Study. An epidemiological investigation of cardiovascular disease. NHLI monograph sections 1-27 1968-1971

5. On the capacity of the Iungs and on the respiratory functions, with a view of establishing a precise and easy method of detecting disease by the spirometer;Med Chir Tr (London),1946

Cited by 54 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3