1. From the Departments of Medicine and Biological Science (H.D., T.I., M.Y., H.K., H.S., K.K.-K., T.T., T.M, E.O., M.A., M.K.) and Ophthalmology (H.A.), Gunma University Graduate School of Medicine, Maebashi, Gunma, Japan; the Institute for Genetic Medicine (L.K.), Department of Biochemistry and Molecular Biology, and Department of Medicine, Keck School of Medicine of the University of Southern California, Los Angeles, Calif.