Response: Mechanism of Action of High-Dose Factor VIIa
Author:
Affiliation:
1. From the Department of Biochemistry, University of Vermont, Burlington.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Cardiology and Cardiovascular Medicine
Reference11 articles.
1. Recombinant factor VIIa (NovoSeven®) as a hemostatic agent
2. Relationship between Factor VII Activity and Clinical Efficacy of Recombinant Factor VIIa Given by Continuous Infusion to Patients with Factor VIII Inhibitors
3. Elective Surgery on Factor VIII Inhibitor Patients Using Continuous Infusion of Recombinant Activated Factor VII
4. Response of Factor VIII and IX-Deficient Blood to Wild Type and High Membrane Affinity Mutant Factor VIIa in an In Vitro Whole Blood Clotting Assay: Possible Correlation to Clinical Outcome
5. Mechanism of factor VIIa–dependent coagulation in hemophilia blood
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1. Unifying the mechanism of recombinant FVIIa action: dose dependence is regulated differently by tissue factor and phospholipids;Blood;2012-07-26
2. Activity and regulation of factor VIIa analogs with increased potency at the endothelial cell surface;Journal of Thrombosis and Haemostasis;2007-02
3. Design, Synthesis, and Biological Evaluation of Peptidomimetic Inhibitors of Factor XIa as Novel Anticoagulants;Journal of Medicinal Chemistry;2006-12-01
4. Disulfide locked variants of factor VIIa with a restricted β-strand conformation have enhanced enzymatic activity;Protein Science;2005-05
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