Design, Synthesis, and Biological Evaluation of Peptidomimetic Inhibitors of Factor XIa as Novel Anticoagulants

Author:

Lin Jian1,Deng Hongfeng1,Jin Lei1,Pandey Pramod1,Quinn Jesse1,Cantin Susan1,Rynkiewicz Michael J.1,Gorga Joan C.1,Bibbins Frank1,Celatka Cassandra A.1,Nagafuji Pamela1,Bannister Thomas D.1,Meyers Harold V.1,Babine Robert E.1,Hayward Neil J.1,Weaver David1,Benjamin Howard1,Stassen Frans1,Abdel-Meguid Sherin S.1,Strickler James E.1

Affiliation:

1. Daiichi Asubio Medical Research Laboratories LLC (DAIAMED), One Kendall Square Building 700, Cambridge, Massachusetts 02139

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Reference45 articles.

1. Response: Mechanism of Action of High-Dose Factor VIIa

2. Jenny, N. S.; Mann, K. G. Coagulation Cascade:  an Overview. InThrombosis and Hemorrhage; Loscalzo, J., Schafer, A. I., Eds.; Williams and Wilkins:  Baltimore, MD, 1998; pp 3−27.

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