Affiliation:
1. From the Andre and Bella Meyer Physiology Laboratory, The Sloan-Kettering Institute and the Medical Service of the Memorial Center for Cancer and Allied Diseases, New York, N. Y.
Abstract
Elevation in serum concentration of the enzyme, glutamic oxalacetic transaminase, (SGO-T), is an accurate index of myocardial infarction in dogs. The enzyme rises in a rough proportion to the extent of myocardial necrosis. The test is a sensitive guide to myocardial injury. Infarcts less than 1 Gm. in weight result in a significant alteration in serum concentration of the enzyme. Concentrations of the enzyme in infarcted muscle are markedly lower than in normal muscle, suggesting that seepage through damaged cells causes the rise in serum concentration. Experimental and clinical myocardial injury result in similar abnormalities.
Publisher
Ovid Technologies (Wolters Kluwer Health)
Subject
Physiology (medical),Cardiology and Cardiovascular Medicine
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