Serum Transaminase Levels in Experimental Myocardial Infarction-Reference-Cited by-同舟云学术

Serum Transaminase Levels in Experimental Myocardial Infarction

Published:1955-05 Issue:5 Volume:11 Page:711-713
ISSN:0009-7322
Container-title:Circulation
language:en
Short-container-title:Circulation

Author:

AGRESS CLARENCE M.¹,JACOBS HOWARD I.¹,GLASSNER HARVEY F.¹,LEDERER MARIANNE A.¹,CLARK WM. G.¹,WROBLEWSKI FELIX¹,KARMEN ARTHUR¹,LADUE JOHN S.¹

Affiliation:

1. From the Cardiovascular and Pharmacology Laboratories, Veterans Administration Center, Los Angeles, and the Departments of Medicine and Physiological Chemistry, University of California-Medical Center, Los Angeles; and the Sloan-Kettering Institute and Department of Medicine, Memorial Center, New York.

Abstract

Serum glutamic oxalacetic transaminase concentrations rise sharply after myocardial infarction produced by bead embolization of the coronary tree in the closed chest dog. The peak concentration is reached in 9 to 23 hours post injury. Rises 20 to 30 times greater than normal may be obtained and are directly correlated with the amount of infarction estimated at autopsy. Serial serum transaminase levels may provide a clinical tool to supplement the electrocardiogram in the diagnosis of acute myocardial infarction as well as provide a roughly quantitative estimate of the amount of myocardium involved.

Publisher

Ovid Technologies (Wolters Kluwer Health)

Subject

Physiology (medical),Cardiology and Cardiovascular Medicine

Link

https://www.ahajournals.org/doi/pdf/10.1161/01.CIR.11.5.711

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