Low‐Field Portable Magnetic Resonance Imaging for Post‐Thrombectomy Assessment of Ongoing Brain Injury

Author:

Sujijantarat Nanthiya1,Koo Andrew B.1,Jambor Ivan23,Malhotra Ajay2,Mazurek Mercy H.4,Parasuram Nethra4,Yadlapalli Vineetha4,Chavva Isha R.4,Lalwani Dheeraj4,Zabinska Julia4,Roy Joanna M.1,Antonios Joseph P.1,Elsamadicy Aladine A.1,Renedo Daniela1,Hebert Ryan M.1,Schindler Joseph L.4,Gilmore Emily J.4,Sansing Lauren H.4,de Havenon Adam4,Olexa Madelynne4,Schiff Steven J.1,Iglesias Juan Eugenio5,Rosen Matthew5,Kimberly William Taylor6,Petersen Nils H.4,Sheth Kevin N.4,Matouk Charles C.1ORCID

Affiliation:

1. Department of Neurosurgery Yale School of Medicine New Haven CT

2. Department of Radiology Yale School of Medicine New Haven CT

3. Department of Radiology University of Turku Turku Finland

4. Department of Neurology Yale School of Medicine New Haven CT

5. Department of Radiology Massachusetts General Hospital Harvard Medical School Boston MA

6. Department of Neurology Massachusetts General Hospital Harvard Medical School Boston MA

Abstract

Background Timely imaging is essential for patients undergoing mechanical thrombectomy (MT). Our objective was to evaluate the safety and feasibility of low‐field portable magnetic resonance imaging (pMRI) for bedside evaluation following MT. Methods Patients with suspected large‐vessel occlusion undergoing MT were screened for eligibility. All pMRI examinations were conducted in the standard ferromagnetic environment of the interventional radiology suite. Clinical characteristics, procedural details, and pMRI features were collected. Subsequent high‐field conventional MRI within 72±12 hours was analyzed. If a conventional MRI was not available for comparison, computed tomography within the same time frame was used for validation. Results Twenty‐four patients were included (63% women; median age, 76 years [interquartile range, 69–84 years]). MT was performed with a median access to revascularization time of 15 minutes (interquartile range, 8–19 minutes), and with a successful outcome as defined by a thrombolysis in cerebral infarction score of ≥2B in 90% of patients. The median time from the end of the procedure to pMRI was 22 minutes (interquartile range, 16–32 minutes). The median pMRI examination time was 30 minutes (interquartile range, 17–33 minutes). Of 23 patients with available subsequent imaging, 9 had infarct progression compared with immediate post‐MT pMRI and 14 patients did not have progression of their infarct volume. There was no adverse event related to the examination. Conclusion Low‐field pMRI is safe and feasible in a post‐MT environment and enables timely identification of ischemic changes in the interventional radiology suite. This approach can facilitate the assessment of baseline infarct burden and may help guide physiological interventions following MT.

Publisher

Ovid Technologies (Wolters Kluwer Health)

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